TripSit · Methadone

正文中文为机器翻译，仅供参考；专业内容以折叠的原文为准。

详情

分类

阿片类 习惯形成 抑制剂 常规

后遗时间

1-48 小时

剂量

口服

常规

10-20mg

轻度

5-10mg

强效

20-35mg+

效应

Euphoria Dry Mouth Mood lift Itchiness Relaxant Constipation Pupil constriction Analgesia

起效时间

45-120 分钟

相关链接

经验报告

https://www.erowid.org/experiences/subs/exp_Methadone.shtml

名称

methadone

通用名

Methadone

属性

后遗效应

1–48 小时.

avoid

All other CNS depressants.

生物利用度

Oral 70-90% | Rectal (aqueous liquid) ~80%

分类

阿片类 习惯形成 抑制剂 常规

剂量

Light: 5-10mg Common: 10-20mg Strong: 20-35mg+ NOTE: these doses are not intended for opioid naïve users. 30mg could be lethal for an opioid naïve user. Please note opioid naïve refers to recent usage, not opioid experience. It is recommended, as always, to start low and increase dosage /slowly/

持续

Oral 6–12 小时. NOTE: The duration may last much longer depending on a variety of factors, such as physical and mental drug dependence.

效应

Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.

half-life

12–18 小时 on the first dose 13-47 on concurrent

起效

45–120 分钟.

摘要

An opioid drug used as an analgesic and is often used during detoxification of other opioids. There are a variety of reasons for this such as methadone's longer half-life duration.

来源

general

Methadone trials have proven successful in treating Heroin addiction - http://jamanetwork.com/journals/jama/article-abstract/656315 Pharmacogenetics of chronic pain management - https://doi.org/10.1016/j.clinbiochem.2014.05.065