TripSit · diphenhydramine + ketamine

正文中文为机器翻译，仅供参考；专业内容以折叠的原文为准。

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备注

这两种物质都会增强另一种物质引起的共济失调和镇静作用，高剂量时可能会导致意外的意识丧失。在失去知觉时，如果不处于恢复姿势，则有呕吐物误吸的风险。较高剂量的氯胺酮很可能会增加 DPH 的谵妄作用，并且会大大增加受伤、躁狂和精神病的风险。 Medical dosages of both substances are unlikely to cause concern.

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Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Ketamine has a high likelihood of increasing DPH's deliriant effects at higher dosages and can greatly increase the risk of injury, mania, and psychosis. Medical dosages of both substances are unlikely to cause concern.

来源

author

Bylund, W., Delahanty, L., & Cooper, M.

标题

The Case of Ketamine Allergy. Clinical Practice and Cases in Emergency Medicine, 1(4), 323–325. (2017)

链接

https://doi.org/10.5811/cpcem.2017.7.34405

author

Clark, J. H., Meltzer, E. O., & Naclerio, R. M.

标题

Diphenhydramine: It is time to say a final goodbye. World Allergy Organization Journal, 18(2), 101027. (2025)

链接

https://doi.org/10.1016/j.waojou.2025.101027

author

Rosenbaum, S. B., Gupta, V., Patel, P., & Palacios, J. L.

标题

Ketamine. In StatPearls. StatPearls Publishing. (2025)

链接

http://www.ncbi.nlm.nih.gov/books/NBK470357/

author

Sicari, V., Patel, P., & Zabbo, C. P.

标题

Diphenhydramine. In StatPearls. StatPearls Publishing. (2025)

链接

http://www.ncbi.nlm.nih.gov/books/NBK526010/

风险等级

危险（应避免） （Dangerous）

物质 A

diphenhydramine

物质 B

氯胺酮