PsychonautWiki · Serotonin-norepinephrine reuptake inhibitor

Serotonin–norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressant drugs which are used in the treatment of major depressive disorder (MDD). They are sometimes also used to treat anxiety disorders, obsessive-compulsive disorder (OCD), attention-deficit hyperactivity disorder (ADHD), chronic neuropathic pain, and fibromyalgia syndrome (FMS), and for the relief of menopausal symptoms. SNRIs are monoamine reuptake inhibitors; specifically, they are inhibitors of the reuptake of serotonin and norepinephrine. These neurotransmitters are known to play a significant role in mood regulation. SNRIs can be contrasted with the more widely used selective serotonin reuptake inhibitors (SSRIs), which primarily act on serotonin.