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正文中文为机器翻译，仅供参考；专业内容以折叠的原文为准。
- 详情
- 备注
由于 5-MeO-xxT 药物的刺激作用和高剂量普瑞巴林的癫痫发作问题，应谨慎使用。普瑞巴林可以减少 5-MeO-xxT 药物的血管收缩、焦虑和其他副作用。此外，普瑞巴林可能会增加 5-MeO-xxT 药物抑制和受伤风险。
查看原文
Caution should be given due to 5-MeO-xxT drugs stimulating effects and pregabalin’s seizure concerns at higher dosages. Pregabalin may reduce the vasoconstriction, anxiety, and other side effects of 5-MeO-xxT drugs. Additionally, Pregabalin may increase 5-MeO-xxT drugs inhibition and risk of injury.
- 来源
- author
- Altair. (n.d.-a)
- 标题
- Pregabalin (Lyrica) - Erowid Exp - “Heart Arrhythmia, Seizure : Not Recreational.”
- 链接
- https://www.erowid.org/experiences/exp.php?ID=69917
- author
- Altuncı, Y. A., Aydoğdu, M., Açıkgöz, E., Güven, Ü., Düzağaç, F., Atasoy, A., Dağlıoğlu, N., & Akgür, S. A. (2021)
- 标题
- New Psychoactive Substance 5-MeO-MiPT In vivo Acute Toxicity and Hystotoxicological Study. Balkan Medical Journal, 38(1), 34–42.
- 链接
- https://doi.org/10.4274/balkanmedj.galenos.2020.2019.11.68
- author
- Barker-Haliski, M., & White, H. S. (2015)
- 标题
- Glutamatergic Mechanisms Associated with Seizures and Epilepsy. Cold Spring Harbor Perspectives in Medicine, 5(8), a022863.
- 链接
- https://doi.org/10.1101/cshperspect.a022863
- author
- Ben-Menachem, E. (2004)
- 标题
- Pregabalin pharmacology and its relevance to clinical practice. Epilepsia, 45 Suppl 6, 13–18.
- 链接
- https://doi.org/10.1111/j.0013-9580.2004.455003.x
- author
- Douke, R. (n.d.)
- 标题
- Pregabalin & Tramadol - Erowid Exp - “Grand Mal Seizures.”
- 链接
- https://www.erowid.org/experiences/exp.php?ID=83232
- author
- French, J., Kwan, P., Fakhoury, T., Pitman, V., DuBrava, S., Knapp, L., & Yurkewicz, L. (2014)
- 标题
- Pregabalin monotherapy in patients with partial-onset seizures. Neurology, 82(7), 590–597.
- 链接
- https://doi.org/10.1212/WNL.0000000000000119
- author
- Gayatri, N. A., & Livingston, J. H. (2006)
- 标题
- Aggravation of epilepsy by anti-epileptic drugs. Developmental Medicine and Child Neurology, 48(5), 394–398.
- 链接
- https://doi.org/10.1017/S0012162206000843
- author
- Hitchings, A. W. (2016)
- 标题
- Drugs that lower the seizure threshold. Adverse Drug Reaction Bulletin, 298(1), 1151–1154.
- 链接
- https://doi.org/10.1097/FAD.0000000000000016
- author
- Isoardi, K. Z., Polkinghorne, G., Harris, K., & Isbister, G. K. (2020)
- 标题
- Pregabalin poisoning and rising recreational use: a retrospective observational series. British Journal of Clinical Pharmacology, 86(12), 2435–2440.
- 链接
- https://doi.org/10.1111/bcp.14348
- author
- Kumar, N., Laferriere, A., Yu, J. S. C., Leavitt, A., & Coderre, T. J. (2010)
- 标题
- Evidence that pregabalin reduces neuropathic pain by inhibiting the spinal release of glutamate. Journal of Neurochemistry, 113(2), 552–561.
- 链接
- https://doi.org/10.1111/j.1471-4159.2010.06625.x
- author
- Reckweg, J. T., Uthaug, M. V., Szabo, A., Davis, A. K., Lancelotta, R., Mason, N. L., & Ramaekers, J. G. (2022)
- 标题
- The clinical pharmacology and potential therapeutic applications of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT). Journal of Neurochemistry, 162(1), 128–146.
- 链接
- https://doi.org/10.1111/jnc.15587
- author
- Rickli, A., Moning, O. D., Hoener, M. C., & Liechti, M. E. (2016)
- 标题
- Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens. European Neuropsychopharmacology: The Journal of the European College of Neuropsychopharmacology, 26(8), 1327–1337.
- 链接
- https://doi.org/10.1016/j.euroneuro.2016.05.001
- author
- Sean. (n.d.-b)
- 标题
- Pregabalin - Erowid Exp - “Stay Away.”
- 链接
- https://www.erowid.org/experiences/exp.php?ID=67302
- author
- Slocum, G. W., Schult, R. F., Gorodetsky, R. M., Wiegand, T. J., Kamali, M., & Acquisto, N. M. (2018)
- 标题
- Pregabalin and paradoxical reaction of seizures in a large overdose. Toxicology Communications, 2(1), 19–20.
- 链接
- https://doi.org/10.1080/24734306.2018.1458465
- author
- Soto-Angona, Ó., Fortea, A., Fortea, L., Martínez-Ramírez, M., Santamarina, E., López, F. J. G., Knudsen, G. M., & Ona, G. (2024)
- 标题
- Do classic psychedelics increase the risk of seizures? A scoping review. European Neuropsychopharmacology, 85, 35–42.
- 链接
- https://doi.org/10.1016/j.euroneuro.2024.05.002
- 风险等级
- 谨慎 （Caution）
- 物质 A
- 5-meo-xxt
- 物质 B
- pregabalin
来源与许可
TripSit · 药物资料
TripSit 数据规则：仅限非商业使用，需署名并在每个展示页附来源链接；组合数据仅为快速参考，需结合个体研究判断。
Reference snapshot, not a forum post. Source: TripSit. Noncommercial reuse with TripSit attribution and a source link on every display page; combination data is a quick reference requiring further individual research. https://wiki.tripsit.me/wiki/Factsheets ; https://wiki.tripsit.me/wiki/Drug_combinations . The package.json ISC software tag does not replace these data-specific terms.
Raw source: https://raw.githubusercontent.com/TripSit/drugs/83670cb6bc8863615fcb9be081c87f061b42dea4/combos.json
Fetched at: 2026-10-23T07:01:06.728397+00:00
Record key: combination:["5-meo-xxt","pregabalin"]
来源主页：https://wiki.tripsit.me/wiki/Factsheets
组合说明：https://wiki.tripsit.me/wiki/Drug_combinations