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正文中文为机器翻译，仅供参考；专业内容以折叠的原文为准。
- 详情
- 备注
由于 DOx 药物的刺激作用和高剂量普瑞巴林的癫痫发作问题，应谨慎使用。普瑞巴林可以减少 DOx 药物的血管收缩、焦虑和其他副作用。此外，普瑞巴林可能会增加 DOx 药物的抑制作用和受伤风险。
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Caution should be given due to DOx drugs stimulating effects and pregabalin’s seizure concerns at higher dosages. Pregabalin may reduce the vasoconstriction, anxiety, and other side effects of DOx drugs. Additionally, Pregabalin may increase DOx drugs inhibition and risk of injury.
- 来源
- author
- ScienceDirect Topics (n.d.)
- 标题
- 2,5-Dimethoxy-4-iodoamphetamine - an overview
- 链接
- https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/2-5-dimethoxy-4-iodoamphetamine
- author
- Altair. (n.d.-a)
- 标题
- Pregabalin (Lyrica) - Erowid Exp - “Heart Arrhythmia, Seizure : Not Recreational.”
- 链接
- https://www.erowid.org/experiences/exp.php?ID=69917
- author
- Barker-Haliski, M., & White, H. S. (2015)
- 标题
- Glutamatergic Mechanisms Associated with Seizures and Epilepsy. Cold Spring Harbor Perspectives in Medicine, 5(8), a022863.
- 链接
- https://doi.org/10.1101/cshperspect.a022863
- author
- Barnett, R. Y., Baker, D. D., Kelly, N. E., McGuire, C. E., Fassette, T. C., & Gorniak, J. M. (2014)
- 标题
- A Fatal Intoxication of 2,5-Dimethoxy-4-Chloroamphetamine: A Case Report. Journal of Analytical Toxicology, 38(8), 589–591.
- 链接
- https://doi.org/10.1093/jat/bku087
- author
- Ben-Menachem, E. (2004)
- 标题
- Pregabalin pharmacology and its relevance to clinical practice. Epilepsia, 45 Suppl 6, 13–18.
- 链接
- https://doi.org/10.1111/j.0013-9580.2004.455003.x
- author
- Burish, M. J., Thoren, K. L., Madou, M., Toossi, S., & Shah, M. (2015)
- 标题
- Hallucinogens Causing Seizures? A Case Report of the Synthetic Amphetamine 2,5-Dimethoxy-4-Chloroamphetamine. The Neurohospitalist, 5(1), 32–34.
- 链接
- https://doi.org/10.1177/1941874414528939
- author
- Douke, R. (n.d.)
- 标题
- Pregabalin & Tramadol - Erowid Exp - “Grand Mal Seizures.”
- 链接
- https://www.erowid.org/experiences/exp.php?ID=83232
- author
- French, J., Kwan, P., Fakhoury, T., Pitman, V., DuBrava, S., Knapp, L., & Yurkewicz, L. (2014)
- 标题
- Pregabalin monotherapy in patients with partial-onset seizures. Neurology, 82(7), 590–597.
- 链接
- https://doi.org/10.1212/WNL.0000000000000119
- author
- Gayatri, N. A., & Livingston, J. H. (2006)
- 标题
- Aggravation of epilepsy by anti-epileptic drugs. Developmental Medicine and Child Neurology, 48(5), 394–398.
- 链接
- https://doi.org/10.1017/S0012162206000843
- author
- Hitchings, A. W. (2016)
- 标题
- Drugs that lower the seizure threshold. Adverse Drug Reaction Bulletin, 298(1), 1151–1154.
- 链接
- https://doi.org/10.1097/FAD.0000000000000016
- author
- Isoardi, K. Z., Polkinghorne, G., Harris, K., & Isbister, G. K. (2020)
- 标题
- Pregabalin poisoning and rising recreational use: a retrospective observational series. British Journal of Clinical Pharmacology, 86(12), 2435–2440.
- 链接
- https://doi.org/10.1111/bcp.14348
- author
- Jacob, P., & Shulgin, A. T. (1994)
- 标题
- Structure-activity relationships of the classic hallucinogens and their analogs. NIDA Research Monograph, 146, 74–91.
- 链接
- https://pubmed.ncbi.nlm.nih.gov/8742795/
- author
- Kumar, N., Laferriere, A., Yu, J. S. C., Leavitt, A., & Coderre, T. J. (2010)
- 标题
- Evidence that pregabalin reduces neuropathic pain by inhibiting the spinal release of glutamate. Journal of Neurochemistry, 113(2), 552–561.
- 链接
- https://doi.org/10.1111/j.1471-4159.2010.06625.x
- author
- Luethi, D., Rudin, D., Hoener, M. C., & Liechti, M. E. (2022)
- 标题
- Monoamine Receptor and Transporter Interaction Profiles of 4‐Alkyl‐Substituted 2,5‐Dimethoxyamphetamines. The FASEB Journal, 36(S1), fasebj.2022.36.S1.R2691.
- 链接
- https://doi.org/10.1096/fasebj.2022.36.S1.R2691
- author
- Sean. (n.d.-b)
- 标题
- Pregabalin - Erowid Exp - “Stay Away.”
- 链接
- https://www.erowid.org/experiences/exp.php?ID=67302
- author
- Slocum, G. W., Schult, R. F., Gorodetsky, R. M., Wiegand, T. J., Kamali, M., & Acquisto, N. M. (2018)
- 标题
- Pregabalin and paradoxical reaction of seizures in a large overdose. Toxicology Communications, 2(1), 19–20.
- 链接
- https://doi.org/10.1080/24734306.2018.1458465
- author
- Trout, K., & Daley, P. F. (2024)
- 标题
- The origin of 2,5‐dimethoxy‐4‐methylamphetamine (DOM, STP). Drug Testing and Analysis, 16(12), 1496–1508.
- 链接
- https://doi.org/10.1002/dta.3667
- 风险等级
- 谨慎 （Caution）
- 物质 A
- dox
- 物质 B
- pregabalin
来源与许可
TripSit · 药物资料
TripSit 数据规则：仅限非商业使用，需署名并在每个展示页附来源链接；组合数据仅为快速参考，需结合个体研究判断。
Reference snapshot, not a forum post. Source: TripSit. Noncommercial reuse with TripSit attribution and a source link on every display page; combination data is a quick reference requiring further individual research. https://wiki.tripsit.me/wiki/Factsheets ; https://wiki.tripsit.me/wiki/Drug_combinations . The package.json ISC software tag does not replace these data-specific terms.
Raw source: https://raw.githubusercontent.com/TripSit/drugs/83670cb6bc8863615fcb9be081c87f061b42dea4/combos.json
Fetched at: 2026-10-23T07:01:06.728397+00:00
Record key: combination:["dox","pregabalin"]
来源主页：https://wiki.tripsit.me/wiki/Factsheets
组合说明：https://wiki.tripsit.me/wiki/Drug_combinations