本条目为第三方公开资料的归档，仅用于学术研究与科普，不构成任何操作指导或医学建议；物质处理涉及法律与健康风险，请在专业、合法的条件下自行核验。
正文中文为机器翻译，仅供参考；专业内容以折叠的原文为准。
- 详情
- 别名
- imovane zimovane
- 分类
- 抑制剂 习惯形成 常规
- 后遗时间
- 1-12 小时
- 剂量
- 口服
- 常规
- 5-7.5mg
- 重剂量
- 15-22.5mg
- 轻度
- 3.5-5mg
- 强效
- 7.5-15mg
- 阈值
- 3.5mg
- 持续时间
- 3.5-9 小时
- 效应
- Lethargy tiredness a dreamlike state while awake can induce heavy sleep
- 起效时间
- 15 分钟
- 名称
- zopiclone
- 通用名
- Zopiclone
- 属性
- 后遗效应
- 1–12 小时.
- 别名
- imovane zimovane
- 分类
- 抑制剂 习惯形成 常规
- chemistry
- IUPAC: (RS)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate | Formula: C17H17ClN6O3 | Molecular Mass: 388.808 g/mol
- contraindications
- Liver disease, myasthenia gravis, severe chronic bronchitis, emphysema, sleep apnea, thyroid gland abnormalities, trimipramine, caffeine, alcohol, erythromycin, itraconazole, rifampicin, phenytoin, carbamazepine, ketoconazole, sulfaphenazole, and nefazodone
- 剂量
- Oral Threshold: 3.5mg Light: 3.5-5mg Common: 5-7.5mg Strong: 7.5-15mg Heavy: 15-22.5mg
- 持续
- 3.5–9 小时
- 效应
- Lethargy, tiredness, a dreamlike state while awake, can induce heavy sleep.
- legal
- Australia: Prescription Only (S4) | United Kingdom: Controlled Drug (POM) | United States: Schedule IV
- 起效
- 15–30 分钟 (on empty stomach)
- pharmacokinetics
- Protein Binding: 45 - 80% | Metabolism: various cytochrome P450 liver enzymes | Excretion: respiration (~50%) and urine (7 - 10 %)
- pharmacology
- GABA-A receptor positive allosteric modulator; Benzodiazepine receptor agonist
- 摘要
A nonbenzodiazepine sedative sleep aid (Z-drug) which can have hallucinogenic effects if taken while awake. The drug is reported to cause users to have a metallic taste in the mouth for ~12h. The drug has been reported in cases to influence certain users to black out, redose excessively, and undertake dangerous activities such as driving.
- 效应
- Amnesia
- https://psychonautwiki.org/wiki/Amnesia
- Anxiety suppression
- https://psychonautwiki.org/wiki/Anxiety_suppression
- Disinhibition
- https://psychonautwiki.org/wiki/Disinhibition
- Dizziness
- https://psychonautwiki.org/wiki/Dizziness
- Information processing suppression
- https://psychonautwiki.org/wiki/Information_processing_suppression
- Motor control loss
- https://psychonautwiki.org/wiki/Motor_control_loss
- Muscle relaxation
- https://psychonautwiki.org/wiki/Muscle_relaxation
- Respiratory depression
- https://psychonautwiki.org/wiki/Respiratory_depression
- Sedation
- https://psychonautwiki.org/wiki/Sedation
- Thought deceleration
- https://psychonautwiki.org/wiki/Thought_deceleration
- 来源
- general
- Dependence potential of zopiclone studied in monkeys - http://www.ncbi.nlm.nih.gov/pubmed/6892368
来源与许可
TripSit · 药物资料
TripSit 数据规则：仅限非商业使用，需署名并在每个展示页附来源链接；组合数据仅为快速参考，需结合个体研究判断。
Reference snapshot, not a forum post. Source: TripSit. Noncommercial reuse with TripSit attribution and a source link on every display page; combination data is a quick reference requiring further individual research. https://wiki.tripsit.me/wiki/Factsheets ; https://wiki.tripsit.me/wiki/Drug_combinations . The package.json ISC software tag does not replace these data-specific terms.
Raw source: https://raw.githubusercontent.com/TripSit/drugs/83670cb6bc8863615fcb9be081c87f061b42dea4/drugs.json
Fetched at: 2026-10-23T07:01:06.728397+00:00
Record key: drug:zopiclone
来源主页：https://wiki.tripsit.me/wiki/Factsheets
组合说明：https://wiki.tripsit.me/wiki/Drug_combinations