TripSit · tramadol + pregabalin

正文中文为机器翻译，仅供参考；专业内容以折叠的原文为准。

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备注

癫痫发作的风险很大。这两种物质都是中枢神经系统抑制剂，彼此之间会产生不可预测的强烈增强作用，增加记忆丧失、严重共济失调和意识丧失的可能性。这种相互作用会造成更大的抑制和受伤的风险。如果用户失去知觉，强烈建议将其置于恢复位置并监测呼吸。据报道，医疗剂量不是一个问题。

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There is a significant risk of seizures. Both substances are CNS depressants, potentiating each other strongly and unpredictably, raising the chances of memory loss, severe ataxia, and unconsciousness. The interaction will cause greater inhibition and risk of injury. If the user falls unconscious it is strongly recommended to put them into the recovery position and monitor breathing. Medical dosages are not reported to be a concern.

来源

author

Altair. (n.d.-a)

标题

Pregabalin (Lyrica) - Erowid Exp - “Heart Arrhythmia, Seizure : Not Recreational.”

链接

https://www.erowid.org/experiences/exp.php?ID=69917

author

Ben-Menachem, E. (2004)

标题

Pregabalin pharmacology and its relevance to clinical practice. Epilepsia, 45 Suppl 6, 13–18.

链接

https://doi.org/10.1111/j.0013-9580.2004.455003.x

author

Boostani, R., & Derakhshan, S. (2012)

标题

Tramadol induced seizure: A 3-year study. Caspian Journal of Internal Medicine, 3(3), 484–487.

链接

https://pubmed.ncbi.nlm.nih.gov/24009919/

author

Douke, R. (n.d.)

标题

Pregabalin & Tramadol - Erowid Exp - “Grand Mal Seizures.”

链接

https://www.erowid.org/experiences/exp.php?ID=83232

author

French, J., Kwan, P., Fakhoury, T., Pitman, V., DuBrava, S., Knapp, L., & Yurkewicz, L. (2014)

标题

Pregabalin monotherapy in patients with partial-onset seizures. Neurology, 82(7), 590–597.

链接

https://doi.org/10.1212/WNL.0000000000000119

author

Hassamal, S., Miotto, K., Dale, W., & Danovitch, I. (2018)

标题

Tramadol: Understanding the Risk of Serotonin Syndrome and Seizures. The American Journal of Medicine, 131(11), 1382.e1-1382.e6.

链接

https://doi.org/10.1016/j.amjmed.2018.04.025

author

Lyndon, A., Audrey, S., Wells, C., Burnell, E. S., Ingle, S., Hill, R., Hickman, M., & Henderson, G. (2017)

标题

Risk to heroin users of polydrug use of pregabalin or gabapentin: Risks in combining gabapentoids with heroin. Addiction, 112(9), 1580–1589.

链接

https://doi.org/10.1111/add.13843

author

Rietjens, S. J., Sikma, M. A., Hunault, C. C., De Lange, D. W., & Hondebrink, L. (2022)

标题

Pregabalin poisoning: Evaluation of dose‐toxicity relationship. British Journal of Clinical Pharmacology, 88(3), 1288–1297.

链接

https://doi.org/10.1111/bcp.15073

author

Sean. (n.d.-b)

标题

Pregabalin - Erowid Exp - “Stay Away.”

链接

https://www.erowid.org/experiences/exp.php?ID=67302

author

Slocum, G. W., Schult, R. F., Gorodetsky, R. M., Wiegand, T. J., Kamali, M., & Acquisto, N. M. (2018)

标题

Pregabalin and paradoxical reaction of seizures in a large overdose. Toxicology Communications, 2(1), 19–20.

链接

https://doi.org/10.1080/24734306.2018.1458465

风险等级

不安全 （Unsafe）

物质 A

曲马多

物质 B

pregabalin