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TripSit · lithium + mxe

TripSit 参考资料 · 相互作用 2026-10-23

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正文中文为机器翻译,仅供参考;专业内容以折叠的原文为准。

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备注

将锂与 MXE 联合使用时,存在发生血清素综合征的风险,因为锂与其他血清素能药物一起使用可诱发血清素综合征,而 MXE 对血清素转运蛋白表现出显着的亲和力。

查看原文

There is a risk of serotonin syndrome when combining Lithium with MXE, as Lithium can induce serotonin syndrome in conjunction with other serotonergic drugs, and MXE has shown a notable affinity for the serotonin transporter.

来源
author
Lenox, R. H., & Hahn, C. G.
标题
Overview of the mechanism of action of lithium in the brain: fifty-year update (2000)
链接
https://pubmed.ncbi.nlm.nih.gov/10826655/
author
Shahani, L.
标题
Venlafaxine Augmentation With Lithium Leading to Serotonin Syndrome (2012)
链接
https://doi.org/10.1176/appi.neuropsych.11080196
author
DeBattista, C., Sofuoglu, M., & Schatzberg, A. F.
标题
Serotonergic synergism: the risks and benefits of combining the selective serotonin reuptake inhibitors with other serotonergic drugs (1998)
链接
https://doi.org/10.1016/S0006-3223(98)00161-9
author
Massot, O.
标题
5-HT1B Receptors: A Novel Target for Lithium: Possible Involvement in Mood Disorders (1999)
链接
https://doi.org/10.1016/S0893-133X(99)00042-1
author
Roth, B. L., Gibbons, S., Arunotayanun, W., Huang, X.-P., Setola, V., Treble, R., & Iversen, L.
标题
The Ketamine Analogue Methoxetamine and 3- and 4-Methoxy Analogues of Phencyclidine Are High Affinity and Selective Ligands for the Glutamate NMDA Receptor (2013)
链接
https://doi.org/10.1371/journal.pone.0059334
author
Marti, M., Talani, G., Miliano, C., Bilel, S., Biggio, F., Bratzu, J., Diana, M., De Luca, M. A., & Fattore, L.
标题
New insights into methoxetamine mechanisms of action: Focus on serotonergic 5-HT2 receptors in pharmacological and behavioral effects in the rat (2021)
链接
https://doi.org/10.1016/j.expneurol.2021.113836
风险等级
危险(应避免) (Dangerous)
物质 A
锂盐
物质 B
mxe
来源与许可

TripSit · 药物资料

TripSit 数据规则:仅限非商业使用,需署名并在每个展示页附来源链接;组合数据仅为快速参考,需结合个体研究判断。

Reference snapshot, not a forum post. Source: TripSit. Noncommercial reuse with TripSit attribution and a source link on every display page; combination data is a quick reference requiring further individual research. https://wiki.tripsit.me/wiki/Factsheets ; https://wiki.tripsit.me/wiki/Drug_combinations . The package.json ISC software tag does not replace these data-specific terms. Raw source: https://raw.githubusercontent.com/TripSit/drugs/83670cb6bc8863615fcb9be081c87f061b42dea4/combos.json Fetched at: 2026-10-23T07:01:06.728397+00:00 Record key: combination:["lithium","mxe"]

来源主页:https://wiki.tripsit.me/wiki/Factsheets
组合说明:https://wiki.tripsit.me/wiki/Drug_combinations