TripSit · diphenhydramine + ssris

正文中文为机器翻译，仅供参考；专业内容以折叠的原文为准。

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备注

休闲剂量的血清素综合征风险很高。据报道，医疗剂量并不是普通人群所关心的问题。合用可能会增加彼此的副作用，如头晕、嗜睡等。

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There is a high risk of serotonin syndrome at recreational dosages. Medical dosages are reported not to be a concern for the general population. The combination may increase each other's side effects, such as dizziness and drowsiness.

来源

author

Clark, J. H., Meltzer, E. O., & Naclerio, R. M.

标题

Diphenhydramine: It is time to say a final goodbye. The World Allergy Organization Journal, 18(2), 101027 (2025)

链接

https://doi.org/10.1016/j.waojou.2025.101027

author

Ener, R. A., Meglathery, S. B., Decker, W. A. V., & Gallagher, R. M.

标题

Serotonin Syndrome and Other Serotonergic Disorders: Table 1. Pain Medicine, 4(1), 63-74 (2003)

链接

https://doi.org/10.1046/j.1526-4637.2003.03005.x

author

Khan, S., Saud, S., Khan, I., Asif, M., Ismail, O., Salam, A., Yang, T. J., & Norville, K. J.

标题

Serotonin Syndrome Presenting with Concomitant Tramadol and Diphenhydramine Use: A Case Report of an Unlikely Side-Effect. Cureus, 10(4), e2421 (2018)

链接

https://doi.org/10.7759/cureus.2421

author

Lane, R., Baldwin, D., & Preskorn, S.

标题

The SSRIs: advantages, disadvantages and differences. Journal of Psychopharmacology, 9(2 Suppl), 163-178 (1995)

链接

https://doi.org/10.1177/0269881195009002011

author

Sproule, B. A., Naranjo, C. A., Brenmer, K. E., & Hassan, P. C.

标题

Selective serotonin reuptake inhibitors and CNS drug interactions. A critical review of the evidence. Clinical Pharmacokinetics, 33(6), 454-471 (1997)

链接

https://doi.org/10.2165/00003088-199733060-00004

author

van Harten, J.

标题

Clinical pharmacokinetics of selective serotonin reuptake inhibitors. Clinical Pharmacokinetics, 24(3), 203-220 (1993)

链接

https://doi.org/10.2165/00003088-199324030-00003

author

Varghese, E., Abate, M. A., Hu, L., Kaplan, J., Kraner, J., Long, D. L., Sorg, M., Mock, A., Greenwald, M., & Andrew, T.

标题

Characterization of Diphenhydramine-Related Accidental Overdose Deaths. Academic Forensic Pathology, 5(1), 105-115 (2015)

链接

https://doi.org/10.23907/2015.011

风险等级

危险（应避免） （Dangerous）

物质 A

diphenhydramine

物质 B

ssris