TripSit · ketamine + lithium

正文中文为机器翻译，仅供参考；专业内容以折叠的原文为准。

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锂可以增强和延长氯胺酮的抗抑郁作用。

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Lithium may enhance and prolong the antidepressant effects of ketamine.

来源

author

Costi, S., Soleimani, L., Glasgow, A., Brallier, J., Spivack, J., Schwartz, J., Levitch, C. F., Richards, S., Hoch, M., Stade, E. C., Welch, A., Collins, K. A., Feder, A., Iosifescu, D. V., Charney, D. S., & Murrough, J. W. (2019)

标题

Lithium continuation therapy following ketamine in patients with treatment resistant unipolar depression: a randomized controlled trial. Neuropsychopharmacology, 44(10), 1812–1819.

链接

https://doi.org/10.1038/s41386-019-0365-0

author

Diazgranados, N., Ibrahim, L., Brutsche, N. E., Newberg, A., Kronstein, P., Khalife, S., Kammerer, W. A., Quezado, Z., Luckenbaugh, D. A., Salvadore, G., Machado-Vieira, R., Manji, H. K., & Zarate, C. A. (2010)

标题

A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression. Archives of General Psychiatry, 67(8), 793.

链接

https://doi.org/10.1001/archgenpsychiatry.2010.90

author

Price, J. B., Yates, C. G., Morath, B. A., Van De Wakker, S. K., Yates, N. J., Butters, K., Frye, M. A., McGee, S. L., & Tye, S. J. (2021)

标题

Lithium augmentation of ketamine increases insulin signaling and antidepressant-like active stress coping in a rodent model of treatment-resistant depression. Translational Psychiatry, 11(1), 1–12.

链接

https://doi.org/10.1038/s41398-021-01716-w

author

Scheuing, L., Chiu, C.-T., Liao, H.-M., & Chuang, D.-M. (2015)

标题

Antidepressant mechanism of ketamine: perspective from preclinical studies. Frontiers in Neuroscience, 9.

链接

https://doi.org/10.3389/fnins.2015.00249

author

Toulany, J., Cunningham, J. E. A., & Nunes, A. (2025)

标题

Overlap and Divergence in Ketamine and Lithium Response in Bipolar Disorder: A Scoping Review. Pharmaceuticals, 18(11), 1662.

链接

https://doi.org/10.3390/ph18111662

author

Wilkowska, A., Szałach, Ł., & Cubała, W. J. (2020)

标题

Ketamine in Bipolar Disorder: A Review. Neuropsychiatric Disease and Treatment, 16, 2707–2717.

链接

https://doi.org/10.2147/NDT.S282208

风险等级

Low Risk & No Synergy

物质 A

氯胺酮

物质 B

锂盐