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正文中文为机器翻译，仅供参考；专业内容以折叠的原文为准。
- 详情
- 备注
这两种物质主要通过 NMDA 拮抗作用发挥作用。目前，没有证据表明可能减少这些影响的机制。
查看原文
Both substances primarily exert their effects through NMDA antagonism. Currently, there is no evidence regarding mechanisms that might reduce these effects.
- 来源
- author
- Jeanna M. Marraffa
- 标题
- Dextromethorphan
- 链接
- https://doi.org/10.1016/B978-0-12-824315-2.00127-5
- author
- Georges Mion, Thierry Villevieille
- 标题
- Ketamine Pharmacology: An Update (Pharmacodynamics and Molecular Aspects, Recent Findings)
- 链接
- https://doi.org/10.1111/cns.12099
- author
- P. Klepstad, P. C. Borchgrevink
- 标题
- Four years' treatment with ketamine and a trial of dextromethorphan in a patient with severe post-herpetic neuralgia
- 链接
- https://doi.org/10.1111/j.1399-6576.1997.tb04709.x
- author
- Stephen M. Stahl
- 标题
- Mechanism of action of dextromethorphan/quinidine: comparison with ketamine
- 链接
- https://doi.org/10.1017/S109285291300062X
- author
- A M Hughes,1 J Rhodes,1 G Fisher,2 M Sellers,3 and J W Growcott1
- 标题
- Assessment of the effect of dextromethorphan and ketamine on the acute nociceptive threshold and wind-up of the second pain response in healthy male volunteers
- 链接
- https://doi.org/10.1046%2Fj.1365-2125.2002.01602.x
- author
- Keiji Tabuchi, MD, Zenya Ito, MD, Shigeki Tsuji, MD, Akira Hara, MD, Tetsuro Wada, MD, Jun Kusakari, MD
- 标题
- Effect of Ketamine, Dextromethorphan, and MK-801 on Cochlear Dysfunction Induced by Transient Ischemia
- 链接
- https://doi.org/10.1177/000348940211100107
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- 物质 A
- 氯胺酮
- 物质 B
- dextromethorphan
来源与许可
TripSit · 药物资料
TripSit 数据规则：仅限非商业使用，需署名并在每个展示页附来源链接；组合数据仅为快速参考，需结合个体研究判断。
Reference snapshot, not a forum post. Source: TripSit. Noncommercial reuse with TripSit attribution and a source link on every display page; combination data is a quick reference requiring further individual research. https://wiki.tripsit.me/wiki/Factsheets ; https://wiki.tripsit.me/wiki/Drug_combinations . The package.json ISC software tag does not replace these data-specific terms.
Raw source: https://raw.githubusercontent.com/TripSit/drugs/83670cb6bc8863615fcb9be081c87f061b42dea4/combos.json
Fetched at: 2026-10-23T07:01:06.728397+00:00
Record key: combination:["ketamine","dextromethorphan"]
来源主页：https://wiki.tripsit.me/wiki/Factsheets
组合说明：https://wiki.tripsit.me/wiki/Drug_combinations