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正文中文为机器翻译,仅供参考;专业内容以折叠的原文为准。
- 详情
- 备注
这种组合存在癫痫发作的显着风险。安非他明会增加呼吸频率,因此需要比正常剂量更高的镇静剂剂量。如果安非他明首先失效,娱乐性剂量的普瑞巴林可能会抑制个体并导致呼吸停止。这两种物质在娱乐剂量下都会导致心脏紧张,并可能导致进一步危险的心脏并发症。据报道,医疗剂量不是一个问题
查看原文
There is a significant risk of seizures from this combination. Amphetamines increase respiration rate allowing for a higher dose of sedatives than normal. If amphetamines wears off first, recreational dosages of pregabalin may overcome the individual and cause respiratory arrest. Both substances at recreational dosages cause strain of the heart and may lead to further dangerous heart complications. Medical dosages are not reported to be a concern
- 来源
- author
- Alo, C., & Kioka, M. J. (2024)
- 标题
- Rave gone wrong: MDMA- induced medical emergency at electrical daisy carnival. A case report. Toxicology Reports, 13, 101739.
- 链接
- https://doi.org/10.1016/j.toxrep.2024.101739
- author
- Altair. (n.d.-a)
- 标题
- Pregabalin (Lyrica) - Erowid Exp - “Heart Arrhythmia, Seizure : Not Recreational.”
- 链接
- https://www.erowid.org/experiences/exp.php?ID=69917
- author
- Ben-Menachem, E. (2004)
- 标题
- Pregabalin pharmacology and its relevance to clinical practice. Epilepsia, 45 Suppl 6, 13–18.
- 链接
- https://doi.org/10.1111/j.0013-9580.2004.455003.x
- author
- Christie, D., Yazar-Klosinski, B., Nosova, E., Kryskow, P., Siu, W., Lessor, D., & Argento, E. (2022)
- 标题
- MDMA-assisted therapy is associated with a reduction in chronic pain among people with post-traumatic stress disorder. Frontiers in Psychiatry, 13.
- 链接
- https://doi.org/10.3389/fpsyt.2022.939302
- author
- Douke, R. (n.d.)
- 标题
- Pregabalin & Tramadol - Erowid Exp - “Grand Mal Seizures.”
- 链接
- https://www.erowid.org/experiences/exp.php?ID=83232
- author
- French, J., Kwan, P., Fakhoury, T., Pitman, V., DuBrava, S., Knapp, L., & Yurkewicz, L. (2014)
- 标题
- Pregabalin monotherapy in patients with partial-onset seizures. Neurology, 82(7), 590–597.
- 链接
- https://doi.org/10.1212/WNL.0000000000000119
- author
- Oskouei, Z., Moshiri, M., Raouf-Rahmati, A., Nemati, A., Bemani Naeini, M., Jomehpour, H., Roohbakhsh, A., Salmasi, Z., & Etemad, L. (2025)
- 标题
- Seizures as an Adverse Effect of Pregabalin Consumption: A Systematic Review. Addiction & Health, 17, 1527.
- 链接
- https://doi.org/10.34172/ahj.1527
- author
- Rietjens, S. J., Sikma, M. A., Hunault, C. C., De Lange, D. W., & Hondebrink, L. (2022)
- 标题
- Pregabalin poisoning: Evaluation of dose‐toxicity relationship. British Journal of Clinical Pharmacology, 88(3), 1288–1297.
- 链接
- https://doi.org/10.1111/bcp.15073
- author
- Sean. (n.d.-b)
- 标题
- Pregabalin - Erowid Exp - “Stay Away.”
- 链接
- https://www.erowid.org/experiences/exp.php?ID=67302
- author
- Slocum, G. W., Schult, R. F., Gorodetsky, R. M., Wiegand, T. J., Kamali, M., & Acquisto, N. M. (2018)
- 标题
- Pregabalin and paradoxical reaction of seizures in a large overdose. Toxicology Communications, 2(1), 19–20.
- 链接
- https://doi.org/10.1080/24734306.2018.1458465
- author
- Vollenweider, F. X., Gamma, A., Liechti, M., & Huber, T. (1998)
- 标题
- Psychological and cardiovascular effects and short-term sequelae of MDMA (“ecstasy”) in MDMA-naïve healthy volunteers. Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology, 19(4), 241–251.
- 链接
- https://doi.org/10.1016/S0893-133X(98)00013-X
- 风险等级
- 不安全 (Unsafe)
- 物质 A
- pregabalin
- 物质 B
- mdma
来源与许可
TripSit · 药物资料
TripSit 数据规则:仅限非商业使用,需署名并在每个展示页附来源链接;组合数据仅为快速参考,需结合个体研究判断。
来源主页:https://wiki.tripsit.me/wiki/Factsheets
组合说明:https://wiki.tripsit.me/wiki/Drug_combinations