TripSit · Methiodone

正文中文为机器翻译，仅供参考；专业内容以折叠的原文为准。

详情

分类

阿片类 习惯形成 抑制剂

后遗时间

6-48 小时

剂量

口服

常规

10-20mg

重剂量

35mg+

轻度

5-10mg

强效

20-35mg

持续时间

6-24 小时

效应

Analgesia Euphoria Sedation Respiratory depression Mood lift Itchiness Dry mouth Pupil constriction Physical relaxation

起效时间

45-120 分钟

相关链接

经验报告

https://www.unodc.org/unodc/en/data-and-analysis/bulletin/bulletin_1963-01-01_1_page005.html

名称

ic-26

通用名

Methiodone

属性

后遗效应

6–48 小时. Drug effects lasting up to 24 小时 were reported in some subjects following single oral doses.

别名

IC-26 I-C-26 WIN 1161-3 Methiodone

avoid

All other CNS depressants.

生物利用度

Oral (exact value unknown).

分类

阿片类 习惯形成 抑制剂

剂量

Light: 5-10mg Common: 10-20mg Strong: 20-35mg+. NOTE: In controlled human studies, single oral doses below approximately 25 mg often produced no definite subjective effects, while morphine-like effects became consistent at higher doses.

持续

Oral 6–24 小时. In human studies, effects were sometimes reported for as long as 24 小时 after a single oral dose.

效应

Analgesia, Euphoria, Sedation, Respiratory depression, Mood lift, Itchiness, Dry mouth, Pupil constriction, Physical relaxation.

half-life

Unknown.

备注

Please be aware that with research chemicals purchased from grey-market vendors, one can never be 100% certain of the actual amount or purity of the active compound. Tread lightly.

起效

45–120 分钟.

摘要

Methiodone (IC-26, WIN 1161-3) is a synthetic opioid analgesic and methadone analogue developed by Sterling Drug Inc. In human studies, low oral doses frequently produced no clear subjective effects, while higher doses induced morphine-like effects with significant inter-individual variability. Twenty-four-hour substitution studies demonstrated that IC-26 effectively suppressed morphine withdrawal, and its addiction liability was concluded to be comparable to morphine.

来源

general

Wolbach AB, Fraser HF. Addiction Liability of I-C-26. Bulletin on Narcotics, 1963. Janssen PA. Synthetic Analgesics Vol. 1. Pergamon Press, 1960. Lednicer D. Central Analgetics. Wiley, 1982. US Patent 2,618,640 – Certain Amino Hydrocarbon Sulfones and Process of Preparation (Archer, Suter, Tullar; Sterling Drug Inc.).