TripSit · opioids + mephedrone

正文中文为机器翻译，仅供参考；专业内容以折叠的原文为准。

详情

备注

兴奋剂会增加呼吸频率，从而允许使用更高剂量的阿片类药物。如果兴奋剂首先消失，那么阿片类药物可能会控制患者并导致呼吸停止。

查看原文

Stimulants increase respiration rate allowing a higher dose of opiates. If the stimulant wears off first then the opiate may overcome the patient and cause respiratory arrest.

来源

author

Cohen, B., Ruth, L. J., & Preuss, C. V. (2025)

标题

Opioid Analgesics. In StatPearls.

链接

http://www.ncbi.nlm.nih.gov/books/NBK459161/

author

Dargan, P. I., Sedefov, R., Gallegos, A., & Wood, D. M. (2011)

标题

The pharmacology and toxicology of the synthetic cathinone mephedrone (4‐methylmethcathinone). Drug Testing and Analysis, 3(7–8), 454–463.

链接

https://doi.org/10.1002/dta.312

author

Hadlock, G. C., Webb, K. M., McFadden, L. M., Chu, P. W., Ellis, J. D., Allen, S. C., Andrenyak, D. M., Vieira-Brock, P. L., German, C. L., Conrad, K. M., Hoonakker, A. J., Gibb, J. W., Wilkins, D. G., Hanson, G. R., & Fleckenstein, A. E. (2011)

标题

4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse. The Journal of Pharmacology and Experimental Therapeutics, 339(2), 530–536.

链接

https://doi.org/10.1124/jpet.111.184119

author

Kehr, J., Ichinose, F., Yoshitake, S., Goiny, M., Sievertsson, T., Nyberg, F., & Yoshitake, T. (2011)

标题

Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5-HT levels in nucleus accumbens of awake rats: Mephedrone increases both DA and 5-HT in rat brain. British Journal of Pharmacology, 164(8), 1949–1958.

链接

https://doi.org/10.1111/j.1476-5381.2011.01499.x

author

Meng, H., Cao, J., Kang, J., Ying, X., Ji, J., Reynolds, W., & Rampe, D. (2012)

标题

Mephedrone, a new designer drug of abuse, produces acute hemodynamic effects in the rat. Toxicology Letters, 208(1), 62–68.

链接

https://doi.org/10.1016/j.toxlet.2011.10.010

author

Pathan, H., & Williams, J. (2012)

标题

Basic opioid pharmacology: an update. British Journal of Pain, 6(1), 11–16.

链接

https://doi.org/10.1177/2049463712438493

风险等级

谨慎 （Caution）

物质 A

阿片类

物质 B

mephedrone