REFERENCE LIBRARY / TripSit

TripSit · Morphine

TripSit 参考资料 · 药物资料 2026-10-23

本条目为第三方公开资料的归档,仅用于学术研究与科普,不构成任何操作指导或医学建议;物质处理涉及法律与健康风险,请在专业、合法的条件下自行核验。

正文中文为机器翻译,仅供参考;专业内容以折叠的原文为准。

详情
分类
阿片类 习惯形成 常规 抑制剂
后遗时间
1-12 小时
剂量
口服
常规
15-20mg
轻度
5mg-10mg
强效
30mg+
效应
Euphoria Dry Mouth Mood lift Itchiness Relaxant Constipation Pupil constriction Analgesia
相关链接
经验报告
https://www.erowid.org/experiences/subs/exp_Morphine.shtml
名称
morphine
通用名
Morphine
属性
后遗效应
1–12 小时.
生物利用度
Oral 30% | Insufflated 15-20% | Rectal 30% NOTE: Chitosan (A linear polysaccharide that helps absorb drugs better) increases the insufflated bioavailabilty to around 60%. Ratio used was 1.3 grams : 6.7 grams (Morphine:Chitosan) Use with caution.
分类
阿片类 习惯形成 常规 抑制剂
剂量
Oral Light: 5mg-10mg Common: 15-20mg Strong: 30mg+
持续
Oral_IR: 4–6 小时 | Oral_ER: 4–10 小时 | Insufflated: 4–5 小时 | Plugged: 3–4 小时 | IV/IM: 2–4 小时.
效应
Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.
起效
Oral_IR: 10–30 分钟 | Oral_ER: 40–80 分钟 | Insufflated: 10–30 分钟 | Plugged: 10–30 分钟 | IV/IM: 0–1 分钟.
摘要

The prototypical opioid drug, a powerful analgesic with euphoric qualities. It is found in the seeds and wax of the plant papaver somniferum (opium poppy). First isolated by Friedrich Sertürner in 1805, named for its sleep-inducing qualities. It is recommended against combining with other CNS depressants and may cause dangerous CNS depression in overdose.

效应
Anxiety suppression
https://psychonautwiki.org/wiki/Anxiety_suppression
Cognitive euphoria
https://psychonautwiki.org/wiki/Cognitive_euphoria
Compulsive redosing
https://psychonautwiki.org/wiki/Compulsive_redosing
Constipation
https://psychonautwiki.org/wiki/Constipation
Cough suppression
https://psychonautwiki.org/wiki/Cough_suppression
Difficulty urinating
https://psychonautwiki.org/wiki/Difficulty_urinating
Internal hallucinations
https://psychonautwiki.org/wiki/Internal_hallucinations
Itchiness
https://psychonautwiki.org/wiki/Itchiness
Nausea
https://psychonautwiki.org/wiki/Nausea
Pain relief
https://psychonautwiki.org/wiki/Pain_relief
Physical euphoria
https://psychonautwiki.org/wiki/Physical_euphoria
Pupil constriction
https://psychonautwiki.org/wiki/Pupil_constriction
Respiratory depression
https://psychonautwiki.org/wiki/Respiratory_depression
Sedation
https://psychonautwiki.org/wiki/Sedation
来源
general
Codeine analgesia is due to codeine-6-glucuronide, not morphine. - https://www.ncbi.nlm.nih.gov/pubmed/11092114 Dextromethorphan potentiates the antinociceptive effects of morphine and the delta-opioid agonist SNC80 in squirrel monkeys. - http://www.ncbi.nlm.nih.gov/pubmed/11805202 Magnesium increases morphine analgesic effect in different experimental models of pain. - http://www.ncbi.nlm.nih.gov/pubmed/11873038 Identification of CYP3A4 and CYP2C8 as the major cytochrome P450 s responsible for morphine N-demethylation in human liver microsomes. - http://www.ncbi.nlm.nih.gov/pubmed/12936704 4-Caffeoyl-1,5-quinide in roasted coffee inhibits [3H]naloxone binding and reverses anti-nociceptive effects of morphine in mice. - http://www.ncbi.nlm.nih.gov/pubmed/15088081 Evaluation the effects of dextromethorphan and midazolam on morphine induced tolerance and dependence in mice. - http://www.ncbi.nlm.nih.gov/pubmed/18819620 Enhancement by grapefruit juice of morphine antinociception. - http://www.ncbi.nlm.nih.gov/pubmed/19043223 Low-Dose Cannabinoid Type 2 Receptor Agonist Attenuates Tolerance to Repeated Morphine Administration via Regulating μ-Opioid Receptor Expression i... - http://www.ncbi.nlm.nih.gov/pubmed/26720619 Influence of a high-fat meal on the absorption of morphine from oral solutions. - http://www.ncbi.nlm.nih.gov/pubmed/2791448 Discriminative stimulus effects of reversible and irreversible opiate agonists: morphine, oxymorphazone and buprenorphine. - http://www.ncbi.nlm.nih.gov/pubmed/6206224 Endogenous codeine and morphine in poor and extensive metabolisers of the CYP2D6 (debrisoquine/sparteine) polymorphism. - http://www.ncbi.nlm.nih.gov/pubmed/8113966 The effect of food intake on the pharmacokinetics of sustained-release morphine sulfate capsules. - http://www.ncbi.nlm.nih.gov/pubmed/9152568
来源与许可

TripSit · 药物资料

TripSit 数据规则:仅限非商业使用,需署名并在每个展示页附来源链接;组合数据仅为快速参考,需结合个体研究判断。

Reference snapshot, not a forum post. Source: TripSit. Noncommercial reuse with TripSit attribution and a source link on every display page; combination data is a quick reference requiring further individual research. https://wiki.tripsit.me/wiki/Factsheets ; https://wiki.tripsit.me/wiki/Drug_combinations . The package.json ISC software tag does not replace these data-specific terms. Raw source: https://raw.githubusercontent.com/TripSit/drugs/83670cb6bc8863615fcb9be081c87f061b42dea4/drugs.json Fetched at: 2026-10-23T07:01:06.728397+00:00 Record key: drug:morphine

来源主页:https://wiki.tripsit.me/wiki/Factsheets
组合说明:https://wiki.tripsit.me/wiki/Drug_combinations