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- 详情
- 分类
- 阿片类 习惯形成 常规 抑制剂
- 后遗时间
- 1-12 小时
- 剂量
- 口服
- 常规
- 15-20mg
- 轻度
- 5mg-10mg
- 强效
- 30mg+
- 效应
- Euphoria Dry Mouth Mood lift Itchiness Relaxant Constipation Pupil constriction Analgesia
- 相关链接
- 经验报告
- https://www.erowid.org/experiences/subs/exp_Morphine.shtml
- 名称
- morphine
- 通用名
- Morphine
- 属性
- 后遗效应
- 1–12 小时.
- 生物利用度
- Oral 30% | Insufflated 15-20% | Rectal 30% NOTE: Chitosan (A linear polysaccharide that helps absorb drugs better) increases the insufflated bioavailabilty to around 60%. Ratio used was 1.3 grams : 6.7 grams (Morphine:Chitosan) Use with caution.
- 分类
- 阿片类 习惯形成 常规 抑制剂
- 剂量
- Oral Light: 5mg-10mg Common: 15-20mg Strong: 30mg+
- 持续
- Oral_IR: 4–6 小时 | Oral_ER: 4–10 小时 | Insufflated: 4–5 小时 | Plugged: 3–4 小时 | IV/IM: 2–4 小时.
- 效应
- Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.
- 起效
- Oral_IR: 10–30 分钟 | Oral_ER: 40–80 分钟 | Insufflated: 10–30 分钟 | Plugged: 10–30 分钟 | IV/IM: 0–1 分钟.
- 摘要
The prototypical opioid drug, a powerful analgesic with euphoric qualities. It is found in the seeds and wax of the plant papaver somniferum (opium poppy). First isolated by Friedrich Sertürner in 1805, named for its sleep-inducing qualities. It is recommended against combining with other CNS depressants and may cause dangerous CNS depression in overdose.
- 效应
- Anxiety suppression
- https://psychonautwiki.org/wiki/Anxiety_suppression
- Cognitive euphoria
- https://psychonautwiki.org/wiki/Cognitive_euphoria
- Compulsive redosing
- https://psychonautwiki.org/wiki/Compulsive_redosing
- Constipation
- https://psychonautwiki.org/wiki/Constipation
- Cough suppression
- https://psychonautwiki.org/wiki/Cough_suppression
- Difficulty urinating
- https://psychonautwiki.org/wiki/Difficulty_urinating
- Internal hallucinations
- https://psychonautwiki.org/wiki/Internal_hallucinations
- Itchiness
- https://psychonautwiki.org/wiki/Itchiness
- Nausea
- https://psychonautwiki.org/wiki/Nausea
- Pain relief
- https://psychonautwiki.org/wiki/Pain_relief
- Physical euphoria
- https://psychonautwiki.org/wiki/Physical_euphoria
- Pupil constriction
- https://psychonautwiki.org/wiki/Pupil_constriction
- Respiratory depression
- https://psychonautwiki.org/wiki/Respiratory_depression
- Sedation
- https://psychonautwiki.org/wiki/Sedation
- 来源
- general
- Codeine analgesia is due to codeine-6-glucuronide, not morphine. - https://www.ncbi.nlm.nih.gov/pubmed/11092114 Dextromethorphan potentiates the antinociceptive effects of morphine and the delta-opioid agonist SNC80 in squirrel monkeys. - http://www.ncbi.nlm.nih.gov/pubmed/11805202 Magnesium increases morphine analgesic effect in different experimental models of pain. - http://www.ncbi.nlm.nih.gov/pubmed/11873038 Identification of CYP3A4 and CYP2C8 as the major cytochrome P450 s responsible for morphine N-demethylation in human liver microsomes. - http://www.ncbi.nlm.nih.gov/pubmed/12936704 4-Caffeoyl-1,5-quinide in roasted coffee inhibits [3H]naloxone binding and reverses anti-nociceptive effects of morphine in mice. - http://www.ncbi.nlm.nih.gov/pubmed/15088081 Evaluation the effects of dextromethorphan and midazolam on morphine induced tolerance and dependence in mice. - http://www.ncbi.nlm.nih.gov/pubmed/18819620 Enhancement by grapefruit juice of morphine antinociception. - http://www.ncbi.nlm.nih.gov/pubmed/19043223 Low-Dose Cannabinoid Type 2 Receptor Agonist Attenuates Tolerance to Repeated Morphine Administration via Regulating μ-Opioid Receptor Expression i... - http://www.ncbi.nlm.nih.gov/pubmed/26720619 Influence of a high-fat meal on the absorption of morphine from oral solutions. - http://www.ncbi.nlm.nih.gov/pubmed/2791448 Discriminative stimulus effects of reversible and irreversible opiate agonists: morphine, oxymorphazone and buprenorphine. - http://www.ncbi.nlm.nih.gov/pubmed/6206224 Endogenous codeine and morphine in poor and extensive metabolisers of the CYP2D6 (debrisoquine/sparteine) polymorphism. - http://www.ncbi.nlm.nih.gov/pubmed/8113966 The effect of food intake on the pharmacokinetics of sustained-release morphine sulfate capsules. - http://www.ncbi.nlm.nih.gov/pubmed/9152568
来源与许可
TripSit · 药物资料
TripSit 数据规则:仅限非商业使用,需署名并在每个展示页附来源链接;组合数据仅为快速参考,需结合个体研究判断。
Reference snapshot, not a forum post. Source: TripSit. Noncommercial reuse with TripSit attribution and a source link on every display page; combination data is a quick reference requiring further individual research. https://wiki.tripsit.me/wiki/Factsheets ; https://wiki.tripsit.me/wiki/Drug_combinations . The package.json ISC software tag does not replace these data-specific terms.
Raw source: https://raw.githubusercontent.com/TripSit/drugs/83670cb6bc8863615fcb9be081c87f061b42dea4/drugs.json
Fetched at: 2026-10-23T07:01:06.728397+00:00
Record key: drug:morphine
来源主页:https://wiki.tripsit.me/wiki/Factsheets
组合说明:https://wiki.tripsit.me/wiki/Drug_combinations