本条目为第三方公开资料的归档，仅用于学术研究与科普，不构成任何操作指导或医学建议；物质处理涉及法律与健康风险，请在专业、合法的条件下自行核验。
正文中文为机器翻译，仅供参考；专业内容以折叠的原文为准。
- 详情
- 别名
- n,n-dmt dimethyltryptamine
- 分类
- 致幻剂 常规
- 相互作用
- 2c-t-x
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- 2c-x
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- 5-meo-xxt
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- alcohol
- 风险等级
- Low Risk & Decrease
- amphetamines
- 备注
兴奋剂会增加焦虑水平和思维循环的风险，从而导致负面经历
查看原文
Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences
- 风险等级
- 谨慎 （Caution）
- amt
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- benzodiazepines
- 风险等级
- Low Risk & Decrease
- caffeine
- 风险等级
- Low Risk & No Synergy
- cannabis
- 备注
大麻与致幻剂具有出乎意料的强烈且有些不可预测的协同作用。
查看原文
Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.
- 风险等级
- 谨慎 （Caution）
- cocaine
- 备注
兴奋剂会增加焦虑水平和思维循环的风险，从而导致负面经历
查看原文
Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences
- 风险等级
- 谨慎 （Caution）
- dextromethorphan
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- diphenhydramine
- 备注
25-50 毫克的 DPH 可能有助于缓解 DMT 的副作用，例如恶心和焦虑。在较高剂量时，应注意不要将谵妄剂 (DPH) 与 DMT 联合使用。除了增加严重伤害和精神创伤的风险外，DMT 还可能增加 DPH 的精神错乱和负面影响。
查看原文
At 25-50mg, DPH may assist with side effects of the DMT such as nausea and anxiety. At higher dosages, the combination of a deliriant (DPH) and DMT is cautioned against. DMT is likely to increase the deliriant and negative effects of DPH, in addition to increasing the risk of severe injury and mental trauma.
- 来源
- author
- Carbonaro, T. M., & Gatch, M. B. (2016)
- 标题
- Neuropharmacology of N,N-Dimethyltryptamine. Brain Research Bulletin, 126(Pt 1), 74–88.
- 链接
- https://doi.org/10.1016/j.brainresbull.2016.04.016
- author
- Chapy, H., Smirnova, M., André, P., Schlatter, J., Chiadmi, F., Couraud, P.-O., Scherrmann, J.-M., Declèves, X., & Cisternino, S. (2014)
- 标题
- Carrier-Mediated Cocaine Transport at the Blood-Brain Barrier as a Putative Mechanism in Addiction Liability. International Journal of Neuropsychopharmacology, 18(1), pyu001.
- 链接
- https://doi.org/10.1093/ijnp/pyu001
- author
- Schaefer, T. S., Patel, P., & Zito, P. M. (2025)
- 标题
- Antiemetic Histamine H1 Receptor Blockers. In StatPearls. StatPearls Publishing.
- 链接
- http://www.ncbi.nlm.nih.gov/books/NBK533003/
- author
- Schifano, F., Chiappini, S., Miuli, A., Mosca, A., Santovito, M. C., Corkery, J. M., Guirguis, A., Pettorruso, M., Di Giannantonio, M., & Martinotti, G. (2021)
- 标题
- Focus on Over-the-Counter Drugs’ Misuse: A Systematic Review on Antihistamines, Cough Medicines, and Decongestants. Frontiers in Psychiatry, 12, 657397.
- 链接
- https://doi.org/10.3389/fpsyt.2021.657397
- author
- Wolfson, A. R., Wong, D., Abrams, E. M., Waserman, S., & Sussman, G. L. (2022)
- 标题
- Diphenhydramine: Time to Move on? The Journal of Allergy and Clinical Immunology: In Practice, 10(12), 3124–3130.
- 链接
- https://doi.org/10.1016/j.jaip.2022.07.018
- 风险等级
- 谨慎 （Caution）
- dox
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- ghb/gbl
- 风险等级
- Low Risk & Decrease
- ketamine
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- lithium
- 备注
有大量报告表明这种组合具有较高的癫痫和精神病风险。
查看原文
There are a large number of reports indicating a high seizure and psychosis risk from this combination.
- 来源
- author
- Sandeep M Nayak, Natalie Gukasyan, Frederick S Barrett , Earth Erowid , Fire Erowid , Roland R Griffiths
- 标题
- Classic Psychedelic Coadministration with Lithium, but Not Lamotrigine, is Associated with Seizures: An Analysis of Online Psychedelic Experience Reports
- 链接
- https://doi.org/10.1055/a-1524-2794
- author
- Erowid
- 标题
- Erowid Interactions
- 链接
- https://erowid.org/chemicals/lsd/lsd_interactions.shtml
- author
- freshboi88
- 标题
- I Was Only on One Dose
- 链接
- https://erowid.org/experiences/exp.php?ID=93681
- author
- YouWerentYouAnymore
- 标题
- Brought My Worst Thoughts to Life
- 链接
- https://erowid.org/experiences/exp.php?ID=110780
- author
- Otto Simonsson, Peper S. Hendricks, Richard Chambers, Walter Osika, Simon B. Goldberg
- 标题
- Prevalence and associations of challenging, difficult or distressing experiences using classic psychedelics
- 链接
- https://doi.org/10.1016/j.jad.2023.01.073
- 风险等级
- 危险（应避免） （Dangerous）
- lsd
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- maois
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- mdma
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- mephedrone
- 备注
兴奋剂会增加焦虑水平和思维循环的风险，从而导致负面经历
查看原文
Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences
- 来源
- author
- Carbonaro, T. M., & Gatch, M. B.
- 标题
- Neuropharmacology of N,N-Dimethyltryptamine. Brain Research Bulletin, 126(Pt 1), 74–88 (2016)
- 链接
- https://doi.org/10.1016/j.brainresbull.2016.04.016
- author
- Erhorn, S.
- 标题
- Dimethyltryptamine. In xPharm: The Comprehensive Pharmacology Reference, 1–4 (2007)
- 链接
- https://doi.org/10.1016/B978-008055232-3.62227-5
- author
- Kehr, J., Ichinose, F., Yoshitake, S., Goiny, M., Sievertsson, T., Nyberg, F., & Yoshitake, T.
- 标题
- Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5-HT levels in nucleus accumbens of awake rats. British Journal of Pharmacology, 164(8), 1949–1958 (2011)
- 链接
- https://doi.org/10.1111/j.1476-5381.2011.01499.x
- author
- Papaseit, E., Moltó, J., Muga, R., Torrens, M., de la Torre, R., & Farré, M.
- 标题
- Clinical Pharmacology of the Synthetic Cathinone Mephedrone. In M. H. Baumann, R. A. Glennon, & J. L. Wiley (Eds.), Neuropharmacology of New Psychoactive Substances (NPS): The Science Behind the Headlines, 313–331 (2017)
- 链接
- https://doi.org/10.1007/7854_2016_61
- author
- Wood, D. M., Davies, S., Greene, S. L., Button, J., Holt, D. W., Ramsey, J., & Dargan, P. I.
- 标题
- Case series of individuals with analytically confirmed acute mephedrone toxicity. Clinical Toxicology, 48(9), 924–927 (2010)
- 链接
- https://doi.org/10.3109/15563650.2010.531021
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- mescaline
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- mushrooms
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- mxe
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- nbomes
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- nitrous
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- opioids
- 风险等级
- Low Risk & No Synergy
- pcp
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- pregabalin
- 备注
普瑞巴林可以减轻 DMT 的焦虑和其他可能的副作用。此外，这种组合可能会增加抑制、头晕和受伤的风险。
查看原文
Pregabalin may reduce the anxiety and other possible side effects of DMT. Additionally, the combination may increase inhibition, dizziness, and risk of injury.
- 来源
- author
- Carbonaro, T. M., & Gatch, M. B. (2016)
- 标题
- Neuropharmacology of N,N-Dimethyltryptamine. Brain Research Bulletin, 126(Pt 1), 74–88.
- 链接
- https://doi.org/10.1016/j.brainresbull.2016.04.016
- author
- Cross, A. L., Viswanath, O., & Sherman, A. L. (2025)
- 标题
- Pregabalin. In StatPearls. StatPearls Publishing.
- 链接
- http://www.ncbi.nlm.nih.gov/books/NBK470341/
- 风险等级
- 低风险 · 协同 （Low Risk & Synergy）
- ssris
- 风险等级
- Low Risk & Decrease
- tramadol
- 备注
众所周知，曲马多可以降低癫痫发作阈值，迷幻药也会引起偶尔的癫痫发作。
查看原文
Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.
- 风险等级
- 不安全 （Unsafe）
- 剂量说明
NOTE: These figures are for 100% effective vaporization methods. Typical methods of vaporization are not 100% effective. The likelihood of having a "breakthrough" experience increases with dosages. Caution is advised.
- 后遗时间
- 15-60 分钟
- 剂量
- 鼻吸
- 常规
- 25-50mg
- 轻度
- 10-25mg
- 强效
- 50-125mg+
- 静脉注射
- 常规
- 15-25mg
- 轻度
- 10-15mg
- 强效
- 25-40mg
- Vapourized
- 常规
- 15-25mg
- 重剂量
- 35mg+
- 轻度
- 10-15mg
- 强效
- 25-35mg
- 阈值
- 5-10mg
- 效应
- immersive experience open eye visuals radical perspective shifting profound life-changing spiritual experiences powerful rushing of sensation change in perception of time auditory hallucinations color shifting hard on lungs when smoking stomach discomfort difficulty integrating experiences overwhelming fear
- 相关链接
- 经验报告
- https://www.erowid.org/experiences/subs/exp_DMT.shtml
- tihkal
- https://www.erowid.org/library/books_online/tihkal/tihkal06.shtml
- 名称
- dmt
- 通用名
- DMT
- 属性
- 后遗效应
- 15–60 分钟
- 别名
- n,n-dmt dimethyltryptamine
- 分类
- 致幻剂 常规
- 剂量
- Vapourised Threshold: 5-10mg Light: 10-15mg Common: 15-25mg Strong: 25-35mg Heavy: 35mg+ | Insufflated Light: 10-25mg Common: 25-50mg Strong: 50-125mg+ | Intravenous Light: 10-15mg Common: 15-25mg Strong: 25-40mg
- 持续
- Vapourized/smoked: 3–10 分钟 | Oral_MAOI: 180–420 分钟 | Insufflated: 45–60 分钟
- 效应
- immersive experience, open eye visuals, radical perspective shifting, profound life-changing spiritual experiences, powerful rushing of sensation, change in perception of time, auditory hallucinations, color shifting, hard on lungs when smoking, stomach discomfort, difficulty integrating experiences, overwhelming fear
- half-life
- 10–20 分钟
- marquis
- Orange
- molecule
- http://www.erowid.org/chemicals/dmt/images/archive/dmt_3d_mid.jpg
- 起效
- Vapourized/smoked: 0–2 分钟 | Oral_MAOI: 20–45 分钟 | Insufflated: 3–5 分钟
- 摘要
A popular and powerful psychedelic, typically used in two ways: either it is vapourised for a short 'breakthrough' experience, or it is taken in combination with an enzyme inhibitor for a long, intense trip (this is also known as ayahuasca or pharmahuasca).
- vaporization
- 60-80C (140-176F)
- 效应
- 8B Geometry - Exposure to inner mechanics of consciousness
- https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness
- Acuity enhancement
- https://psychonautwiki.org/wiki/Acuity_enhancement
- After images
- https://psychonautwiki.org/wiki/After_images
- Analysis enhancement
- https://psychonautwiki.org/wiki/Analysis_enhancement
- Auditory distortion
- https://psychonautwiki.org/wiki/Auditory_distortion
- Auditory enhancement
- https://psychonautwiki.org/wiki/Auditory_enhancement
- Auditory hallucinations
- https://psychonautwiki.org/wiki/Auditory_hallucinations
- Autonomous entities
- https://psychonautwiki.org/wiki/Autonomous_entities
- Changes in gravity
- https://psychonautwiki.org/wiki/Changes_in_gravity
- Colour enhancement
- https://psychonautwiki.org/wiki/Colour_enhancement
- Colour replacement
- https://psychonautwiki.org/wiki/Colour_replacement
- Colour shifting
- https://psychonautwiki.org/wiki/Colour_shifting
- Drifting
- https://psychonautwiki.org/wiki/Drifting
- Emotion enhancement
- https://psychonautwiki.org/wiki/Emotion_enhancement
- Exposure to inner mechanics of consciousness
- https://psychonautwiki.org/wiki/Exposure_to_inner_mechanics_of_consciousness
- External hallucinations
- https://psychonautwiki.org/wiki/External_hallucinations
- Feelings of impending doom
- https://psychonautwiki.org/wiki/Feelings_of_impending_doom
- Geometry
- https://psychonautwiki.org/wiki/Geometry
- Internal hallucinations
- https://psychonautwiki.org/wiki/Internal_hallucinations
- Machinescapes
- https://psychonautwiki.org/wiki/Machinescapes
- Memory suppression
- https://psychonautwiki.org/wiki/Memory_suppression
- Mindfulness
- https://psychonautwiki.org/wiki/Mindfulness
- Novelty enhancement
- https://psychonautwiki.org/wiki/Novelty_enhancement
- Pattern recognition enhancement
- https://psychonautwiki.org/wiki/Pattern_recognition_enhancement
- Personal bias suppression
- https://psychonautwiki.org/wiki/Personal_bias_suppression
- Perspective alterations
- https://psychonautwiki.org/wiki/Perspective_alterations
- Physical euphoria
- https://psychonautwiki.org/wiki/Physical_euphoria
- Pupil dilation
- https://psychonautwiki.org/wiki/Pupil_dilation
- Recursion
- https://psychonautwiki.org/wiki/Recursion
- Rejuvenation
- https://psychonautwiki.org/wiki/Rejuvenation
- Scenarios and plots
- https://psychonautwiki.org/wiki/Scenarios_and_plots
- Scenery slicing
- https://psychonautwiki.org/wiki/Scenery_slicing
- Settings, sceneries, and landscapes
- https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes
- Spirituality enhancement
- https://psychonautwiki.org/wiki/Spirituality_enhancement
- Spontaneous tactile sensations
- https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations
- Subconscious communication
- https://psychonautwiki.org/wiki/Subconscious_communication
- Symmetrical texture repetition
- https://psychonautwiki.org/wiki/Symmetrical_texture_repetition
- Temperature regulation suppression
- https://psychonautwiki.org/wiki/Temperature_regulation_suppression
- Tracers
- https://psychonautwiki.org/wiki/Tracers
- Transformations
- https://psychonautwiki.org/wiki/Transformations
- Unity and interconnectedness
- https://psychonautwiki.org/wiki/Unity_and_interconnectedness
来源与许可
TripSit · 药物资料
TripSit 数据规则：仅限非商业使用，需署名并在每个展示页附来源链接；组合数据仅为快速参考，需结合个体研究判断。
Reference snapshot, not a forum post. Source: TripSit. Noncommercial reuse with TripSit attribution and a source link on every display page; combination data is a quick reference requiring further individual research. https://wiki.tripsit.me/wiki/Factsheets ; https://wiki.tripsit.me/wiki/Drug_combinations . The package.json ISC software tag does not replace these data-specific terms.
Raw source: https://raw.githubusercontent.com/TripSit/drugs/83670cb6bc8863615fcb9be081c87f061b42dea4/drugs.json
Fetched at: 2026-10-23T07:01:06.728397+00:00
Record key: drug:dmt
来源主页：https://wiki.tripsit.me/wiki/Factsheets
组合说明：https://wiki.tripsit.me/wiki/Drug_combinations