TripSit · mxe + pregabalin

正文中文为机器翻译，仅供参考；专业内容以折叠的原文为准。

详情

备注

普瑞巴林和 MXE 可能会协同作用并增加彼此的负面副作用，例如恶心、头晕和意识丧失。由于癫痫发作的担忧，建议谨慎使用任何高于低剂量的剂量，以及针对癫痫发作风险较高和/或行为的个体的所有剂量。

查看原文

Pregabalin and MXE may synergize and increase each other’s negative side effects such as nausea, dizziness, and loss of consciousness. Caution is advised for anything above low dosages due to seizure concerns, and all dosages for individuals with higher risk seizure profiles and or behavior.

来源

author

Anwar, S., Cooper, J., Rahman, J., Sharma, C., & Langford, R. (2019)

标题

Prolonged Perioperative Use of Pregabalin and Ketamine to Prevent Persistent Pain after Cardiac Surgery. Anesthesiology, 131(1), 119–131.

链接

https://doi.org/10.1097/ALN.0000000000002751

author

Arendt-Nielsen, L., Mansikka, H., Staahl, C., Rees, H., Tan, K., Smart, T. S., Monhemius, R., Suzuki, R., & Drewes, A. M. (2011)

标题

A Translational Study of the Effects of Ketamine and Pregabalin on Temporal Summation of Experimental Pain: Regional Anesthesia and Pain Medicine, 36(6), 585–591.

链接

https://doi.org/10.1097/AAP.0b013e31822b0db0

author

Barker-Haliski, M., & White, H. S. (2015)

标题

Glutamatergic Mechanisms Associated with Seizures and Epilepsy. Cold Spring Harbor Perspectives in Medicine, 5(8), a022863.

链接

https://doi.org/10.1101/cshperspect.a022863

author

Ben‐Menachem, E. (2004)

标题

Pregabalin Pharmacology and Its Relevance to Clinical Practice. Epilepsia, 45(s6), 13–18.

链接

https://doi.org/10.1111/j.0013-9580.2004.455003.x

author

French, J., Kwan, P., Fakhoury, T., Pitman, V., DuBrava, S., Knapp, L., & Yurkewicz, L. (2014)

标题

Pregabalin monotherapy in patients with partial-onset seizures: A historical-controlled trial. Neurology, 82(7), 590–597.

链接

https://doi.org/10.1212/WNL.0000000000000119

author

Gayatri, N., & Livingston, J. (2006)

标题

Aggravation of epilepsy by anti‐epileptic drugs. Developmental Medicine & Child Neurology, 48(5), 394–398.

链接

https://doi.org/10.1017/S0012162206000843

author

Hitchings, A. W. (2016)

标题

Drugs that lower the seizure threshold. Adverse Drug Reaction Bulletin, 298(1), 1151–1154.

链接

https://doi.org/10.1097/FAD.0000000000000016

author

Isoardi, K. Z., Polkinghorne, G., Harris, K., & Isbister, G. K. (2020)

标题

Pregabalin poisoning and rising recreational use: a retrospective observational series. British Journal of Clinical Pharmacology, 86(12), 2435–2440.

链接

https://doi.org/10.1111/bcp.14348

author

Kumar, N., Laferriere, A., Yu, J. S. C., Leavitt, A., & Coderre, T. J. (2010)

标题

Evidence that pregabalin reduces neuropathic pain by inhibiting the spinal release of glutamate. Journal of Neurochemistry, 113(2), 552–552.

链接

https://doi.org/10.1111/j.1471-4159.2010.06625.x

author

Marti, M., Talani, G., Miliano, C., Bilel, S., Biggio, F., Bratzu, J., Diana, M., De Luca, M. A., & Fattore, L. (2021)

标题

New insights into methoxetamine mechanisms of action: Focus on serotonergic 5-HT2 receptors in pharmacological and behavioral effects in the rat. Experimental Neurology, 345, 113836.

链接

https://doi.org/10.1016/j.expneurol.2021.113836

author

Martinez, V., Cymerman, A., Ben Ammar, S., Fiaud, J. F., Rapon, C., Poindessous, F., Judet, T., Chauvin, M., Bouhassira, D., Sessler, D., Mazoit, X., & Fletcher, D. (2014)

标题

The analgesic efficiency of combined pregabalin and ketamine for total hip arthroplasty: a randomised, double‐blind, controlled study. Anaesthesia, 69(1), 46–52.

链接

https://doi.org/10.1111/anae.12495

author

Roth, B. L., Gibbons, S., Arunotayanun, W., Huang, X.-P., Setola, V., Treble, R., & Iversen, L. (2013)

标题

The Ketamine Analogue Methoxetamine and 3- and 4-Methoxy Analogues of Phencyclidine Are High Affinity and Selective Ligands for the Glutamate NMDA Receptor. PLoS ONE, 8(3), e59334.

链接

https://doi.org/10.1371/journal.pone.0059334

author

Slocum, G. W., Schult, R. F., Gorodetsky, R. M., Wiegand, T. J., Kamali, M., & Acquisto, N. M. (2018)

标题

Pregabalin and paradoxical reaction of seizures in a large overdose. Toxicology Communications, 2(1), 19–20.

链接

https://doi.org/10.1080/24734306.2018.1458465

author

Zhou, Y., Sun, W., Fu, Y., Wang, J., Fan, J., Liang, Y., Jia, W., & Han, R. (2024)

标题

Effect of esketamine combined with pregabalin on acute postsurgical pain in patients who underwent resection of spinal neoplasms: a randomized controlled trial. Pain, 165(9), e96–e105.

链接

https://doi.org/10.1097/j.pain.0000000000003211

风险等级

谨慎 （Caution）

物质 A

mxe

物质 B

pregabalin