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正文中文为机器翻译,仅供参考;专业内容以折叠的原文为准。
- 详情
- 备注
这两种物质会强烈且不可预测地相互增强,并可能迅速导致昏迷。它们都会增加彼此的副作用,如共济失调、镇静和中枢神经系统抑制。昏厥和记忆丧失显着增加。如果使用者在醉酒状态下失去知觉,且不采取恢复姿势,则存在严重的呕吐物误吸风险。酒精也可能会增加苯海拉明的谵妄作用。还应该注意的是,如果饮酒的人通常对酒精有脸红反应,苯海拉明可能会减少这种反应并掩盖酒精的一些影响。
查看原文
The two substances potentiate each other strongly and unpredictably, and may rapidly lead to unconsciousness. They both increase each other's side effects such as ataxia, sedation, and CNS depression. Blackouts and memory loss are significantly increased. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position. Alcohol may also increase the deliriant effects of diphenhydramine. It should also be noted if the individual consuming alcohol typically has a flushing response to alcohol, diphenhydramine may reduce the reaction and mask some of the effects of the alcohol.
- 来源
- author
- ScienceDirect
- 标题
- Diphenhydramine - an overview (2024)
- 链接
- https://www.sciencedirect.com/topics/chemistry/diphenhydramine
- author
- ScienceDirect
- 标题
- Ethanol - an overview (2024)
- 链接
- https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/ethanol
- author
- Miller, N. S., Goodwin, D. W., Jones, F. C., Gabrielli, W. F., Pardo, M. P., Anand, M. M., & Hall, T. B.
- 标题
- Antihistamine blockade of alcohol-induced flushing in orientals. Journal of Studies on Alcohol, 49(1), 16-20 (1988)
- 链接
- https://doi.org/10.15288/jsa.1988.49.16
- author
- Sicari, V., & Zabbo, C. P.
- 标题
- Diphenhydramine. In StatPearls. StatPearls Publishing (2024)
- 链接
- http://www.ncbi.nlm.nih.gov/books/NBK526010/
- author
- Weathermon, R., & Crabb, D. W.
- 标题
- Alcohol and Medication Interactions. Alcohol Research & Health, 23(1), 40-54 (1999)
- 链接
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761694/
- 风险等级
- 危险(应避免) (Dangerous)
- 物质 A
- diphenhydramine
- 物质 B
- 酒精
来源与许可
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来源主页:https://wiki.tripsit.me/wiki/Factsheets
组合说明:https://wiki.tripsit.me/wiki/Drug_combinations