TripSit · ghb/gbl + pregabalin

正文中文为机器翻译，仅供参考；专业内容以折叠的原文为准。

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备注

这两种物质会强烈且不可预测地相互增强，并可能迅速导致昏迷。它们都会增加彼此的副作用，如共济失调、镇静和中枢神经系统抑制。昏厥和记忆丧失的风险显着增加。如果使用者在醉酒状态下失去知觉，且不采取恢复姿势，则存在严重的呕吐物误吸风险。这种组合会增加癫痫发作的风险。

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The two substances potentiate each other strongly and unpredictably, and may rapidly lead to unconsciousness. They both increase each other's side effects such as ataxia, sedation, and CNS depression. Blackout and memory loss risk is significantly increased. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position. There is an increased risk of seizures from this combination.

来源

author

Cagnin, A., Pompanin, S., Manfioli, V., Briani, C., Zambon, A., Saladini, M., & Dam, M. (2011)

标题

γ-Hydroxybutyric acid-induced psychosis and seizures.

链接

https://doi.org/10.1016/j.yebeh.2011.03.009

author

Castelli, M. P., Ferraro, L., Mocci, I., Carta, F., Carai, M. A. M., Antonelli, T., Tanganelli, S., Cignarella, G., & Gessa, G. L. (2003)

标题

Selective γ‐hydroxybutyric acid receptor ligands increase extracellular glutamate in the hippocampus, but fail to activate G protein and to produce the sedative/hypnotic effect of γ‐hydroxybutyric acid.

链接

https://doi.org/10.1046/j.1471-4159.2003.02037.x

author

Eipe, N., & Penning, J. (2011)

标题

Postoperative Respiratory Depression Associated with Pregabalin: A Case Series and a Preoperative Decision Algorithm.

链接

https://doi.org/10.1155/2011/561604

author

Elliott, S. P., Burke, T., & Smith, C. (2017)

标题

Determining the Toxicological Significance of Pregabalin in Fatalities.

链接

https://doi.org/10.1111/1556-4029.13263

author

Evoy, K. E., Sadrameli, S., Contreras, J., Covvey, J. R., Peckham, A. M., & Morrison, M. D. (2021)

标题

Abuse and Misuse of Pregabalin and Gabapentin: A Systematic Review Update.

链接

https://doi.org/10.1007/s40265-020-01432-7

author

Galloway, G. P., Frederick, S. L., Staggers, F. E., Gonzales, M., Stalcup, S. A., & Smith, D. E. (1997)

标题

Gamma-hydroxybutyrate: an emerging drug of abuse that causes physical dependence.

链接

https://pubmed.ncbi.nlm.nih.gov/9060200/

author

Le, J. K., & Richards, J. R. (2025a)

标题

Gamma-Hydroxybutyrate Toxicity. In StatPearls.

链接

http://www.ncbi.nlm.nih.gov/books/NBK430781/

author

Le, J. K., & Richards, J. R. (2025b)

标题

Gamma-Hydroxybutyrate Toxicity. In StatPearls.

链接

http://www.ncbi.nlm.nih.gov/books/NBK430781/

author

Oskouei, Z., Moshiri, M., Raouf-Rahmati, A., Nemati, A., Bemani Naeini, M., Jomehpour, H., Roohbakhsh, A., Salmasi, Z., & Etemad, L. (2025)

标题

Seizures as an Adverse Effect of Pregabalin Consumption: A Systematic Review.

链接

https://doi.org/10.34172/ahj.1527

author

Venzi, M., Di Giovanni, G., & Crunelli, V. (2014)

标题

A Critical Evaluation of the Gamma‐Hydroxybutyrate (GHB) Model of Absence Seizures.

链接

https://doi.org/10.1111/cns.12337

author

Winters, W. D., & Spooner, C. E. (1965)

标题

Various seizure activities following gamma-hydroxybutyrate.

链接

https://doi.org/10.1016/0028-3908(65)90034-1

风险等级

危险（应避免） （Dangerous）

物质 A

ghb/gbl

物质 B

pregabalin